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Impact of Helicobacter pylori Infection and Its Major Virulence Factor CagA on DNA Damage Repair

Helicobacter pylori infection induces a plethora of DNA damages. Gastric epithelial cells, in order to maintain genomic integrity, require an integrous DNA damage repair (DDR) machinery, which, however, is reported to be modulated by the infection. CagA is a major H. pylori virulence factor, associa...

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Detalles Bibliográficos
Autores principales: Kontizas, Eleftherios, Tastsoglou, Spyros, Karamitros, Timokratis, Karayiannis, Yiannis, Kollia, Panagoula, Hatzigeorgiou, Artemis G., Sgouras, Dionyssios N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765595/
https://www.ncbi.nlm.nih.gov/pubmed/33339161
http://dx.doi.org/10.3390/microorganisms8122007