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Targeted Genome Mining—From Compound Discovery to Biosynthetic Pathway Elucidation

Natural products are an important source of novel investigational compounds in drug discovery. Especially in the field of antibiotics, Actinobacteria have been proven to be a reliable source for lead structures. The discovery of these natural products with activity- and structure-guided screenings h...

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Detalles Bibliográficos
Autores principales: Gummerlich, Nils, Rebets, Yuriy, Paulus, Constanze, Zapp, Josef, Luzhetskyy, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765855/
https://www.ncbi.nlm.nih.gov/pubmed/33352664
http://dx.doi.org/10.3390/microorganisms8122034