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Targeted Genome Mining—From Compound Discovery to Biosynthetic Pathway Elucidation
Natural products are an important source of novel investigational compounds in drug discovery. Especially in the field of antibiotics, Actinobacteria have been proven to be a reliable source for lead structures. The discovery of these natural products with activity- and structure-guided screenings h...
Autores principales: | Gummerlich, Nils, Rebets, Yuriy, Paulus, Constanze, Zapp, Josef, Luzhetskyy, Andriy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765855/ https://www.ncbi.nlm.nih.gov/pubmed/33352664 http://dx.doi.org/10.3390/microorganisms8122034 |
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