Enhancing the Poor Flow and Tableting Problems of High Drug-Loading Formulation of Canagliflozin Using Continuous Green Granulation Process and Design-of-Experiment Approach

Maximization of drug-loading can significantly reduce the size of dosage form and consequently decrease the cost of manufacture. In this research, two challenges were addressed: poor flow and tableting problems of high-drug loading (>70%) formulation of canagliflozin (CNG), by adopting the moistu...

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Detalles Bibliográficos
Autores principales: Almutairy, Bjad K., Khafagy, El-Sayed, Alalaiwe, Ahmed, Aldawsari, Mohammed F., Alshahrani, Saad M., Alsulays, Bader B., Alshetaili, Abdullah S., Alshehri, Sultan M., Fayed, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765871/
https://www.ncbi.nlm.nih.gov/pubmed/33348779
http://dx.doi.org/10.3390/ph13120473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765871/
https://www.ncbi.nlm.nih.gov/pubmed/33348779
http://dx.doi.org/10.3390/ph13120473

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