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Layered Double Hydroxide as a Potent Non-viral Vector for Nucleic Acid Delivery Using Gene-Activated Scaffolds for Tissue Regeneration Applications

Nonviral vectors offer a safe alternative to viral vectors for gene therapy applications, albeit typically exhibiting lower transfection efficiencies. As a result, there remains a significant need for the development of a nonviral delivery system with low cytotoxicity and high transfection efficacy...

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Detalles Bibliográficos
Autores principales: Costard, Lara S., Kelly, Domhnall C., Power, Rachael N., Hobbs, Christopher, Jaskaniec, Sonia, Nicolosi, Valeria, Cavanagh, Brenton L., Curtin, Caroline M., O’Brien, Fergal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765978/
https://www.ncbi.nlm.nih.gov/pubmed/33339452
http://dx.doi.org/10.3390/pharmaceutics12121219