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Layered Double Hydroxide as a Potent Non-viral Vector for Nucleic Acid Delivery Using Gene-Activated Scaffolds for Tissue Regeneration Applications
Nonviral vectors offer a safe alternative to viral vectors for gene therapy applications, albeit typically exhibiting lower transfection efficiencies. As a result, there remains a significant need for the development of a nonviral delivery system with low cytotoxicity and high transfection efficacy...
Autores principales: | Costard, Lara S., Kelly, Domhnall C., Power, Rachael N., Hobbs, Christopher, Jaskaniec, Sonia, Nicolosi, Valeria, Cavanagh, Brenton L., Curtin, Caroline M., O’Brien, Fergal J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765978/ https://www.ncbi.nlm.nih.gov/pubmed/33339452 http://dx.doi.org/10.3390/pharmaceutics12121219 |
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