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APC Mutations Are Not Confined to Hotspot Regions in Early-Onset Colorectal Cancer
SIMPLE SUMMARY: Mutation of the APC gene is a common early event in colorectal cancer, however lower rates have been reported in younger cohorts of colorectal cancer patients. In sporadic cancer, mutations are typically clustered around a mutation cluster region, a narrowly defined hotspot within th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766084/ https://www.ncbi.nlm.nih.gov/pubmed/33352971 http://dx.doi.org/10.3390/cancers12123829 |