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HCV-Associated Exosomes Upregulate RUNXOR and RUNX1 Expressions to Promote MDSC Expansion and Suppressive Functions through STAT3–miR124 Axis

RUNX1 overlapping RNA (RUNXOR) is a long non-coding RNA and plays a pivotal role in the differentiation of myeloid cells via targeting runt-related transcription factor 1 (RUNX1). We and others have previously reported that myeloid-derived suppressor cells (MDSCs) expand and inhibit host immune resp...

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Detalles Bibliográficos
Autores principales: Thakuri, Bal Krishna Chand, Zhang, Jinyu, Zhao, Juan, Nguyen, Lam N., Nguyen, Lam N. T., Schank, Madison, Khanal, Sushant, Dang, Xindi, Cao, Dechao, Lu, Zeyuan, Wu, Xiao Y., Jiang, Yong, El Gazzar, Mohamed, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766103/
https://www.ncbi.nlm.nih.gov/pubmed/33353065
http://dx.doi.org/10.3390/cells9122715