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Improved Cell Selectivity of Pseudin-2 via Substitution in the Leucine-Zipper Motif: In Vitro and In Vivo Antifungal Activity

Several antimicrobial peptides (AMPs) have been discovered, developed, and purified from natural sources and peptide engineering; however, the clinical applications of these AMPs are limited owing to their lack of abundance and side effects related to cytotoxicity, immunogenicity, and hemolytic acti...

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Detalles Bibliográficos
Autores principales: Park, Seong-Cheol, Kim, Heabin, Kim, Jin-Young, Kim, Hyeonseok, Cheong, Gang-Won, Lee, Jung Ro, Jang, Mi-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766124/
https://www.ncbi.nlm.nih.gov/pubmed/33352972
http://dx.doi.org/10.3390/antibiotics9120921