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Detailed Characterization of the Cooperative Binding of Piperine with Heat Shock Protein 70 by Molecular Biophysical Approaches

In this work, for the first time, details of the complex formed by heat shock protein 70 (HSP70) independent nucleotide binding domain (NBD) and piperine were characterized through experimental and computational molecular biophysical methods. Fluorescence spectroscopy results revealed positive coope...

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Detalles Bibliográficos
Autores principales: Zazeri, Gabriel, Povinelli, Ana Paula Ribeiro, Lima, Marcelo de Freitas, Cornélio, Marinônio Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766160/
https://www.ncbi.nlm.nih.gov/pubmed/33353024
http://dx.doi.org/10.3390/biomedicines8120629