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B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma

SIMPLE SUMMARY: Although chemotherapy is associated with high relapse rates and numerous side effects, it is still used as the front line treatment of anaplastic large cell lymphoma (ALCL). Therefore, alternative treatment options for ALCL are needed. In this study, we show that B7-H3 is a novel and...

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Detalles Bibliográficos
Autores principales: Zi, Zhenguo, Zhao, Haihong, Wang, Huanyu, Ma, Xiaojing, Wei, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766167/
https://www.ncbi.nlm.nih.gov/pubmed/33348781
http://dx.doi.org/10.3390/cancers12123815