Improvement of PR8-Derived Recombinant Clade 2.3.4.4c H5N6 Vaccine Strains by Optimization of Internal Genes and H103Y Mutation of Hemagglutinin

Clade 2.3.4.4c H5N6 avian influenza A viruses (AIVs) may have originally adapted to infect chickens and have caused highly pathogenic avian influenza (HPAI) in poultry and human fatalities. Although A/Puerto Rico/8/1934 (H1N1) (PR8)-derived recombinant clade 2.3.4.4c H5N6 vaccine strains have been e...

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Detalles Bibliográficos
Autores principales: An, Se-Hee, Hong, Seung-Min, Son, Seung-Eun, Song, Jin-Ha, Lee, Chung-Young, Choi, Jun-Gu, Lee, Youn-Jeong, Jeong, Jei-Hyun, Kim, Jun-Beom, Song, Chang-Seon, Kim, Jae-Hong, Choi, Kang-Seuk, Kwon, Hyuk-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766170/
https://www.ncbi.nlm.nih.gov/pubmed/33419331
http://dx.doi.org/10.3390/vaccines8040781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766170/
https://www.ncbi.nlm.nih.gov/pubmed/33419331
http://dx.doi.org/10.3390/vaccines8040781

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