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NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

SIMPLE SUMMARY: Malignant melanoma (MM) is the most fatal skin cancer due to its high metastatic potential. Treatment strategies are dramatically changing due to the introduction of BRAF/MEK inhibitors (i) and immunotherapy; however, multiple resistant mechanisms rapidly occur including metabolic re...

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Detalles Bibliográficos
Autores principales: Audrito, Valentina, Messana, Vincenzo Gianluca, Moiso, Enrico, Vitale, Nicoletta, Arruga, Francesca, Brandimarte, Lorenzo, Gaudino, Federica, Pellegrino, Elisa, Vaisitti, Tiziana, Riganti, Chiara, Piva, Roberto, Deaglio, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766175/
https://www.ncbi.nlm.nih.gov/pubmed/33419372
http://dx.doi.org/10.3390/cancers12123855