Melatonin Protects Cholangiocytes from Oxidative Stress-Induced Proapoptotic and Proinflammatory Stimuli via miR-132 and miR-34

Biosynthesis of melatonin by cholangiocytes is essential for maintaining the function of biliary epithelium. However, this cytoprotective mechanism appears to be impaired in primary biliary cholangitis (PBC). MiR-132 has emerged as a mediator of inflammation in chronic liver diseases. The effect of...

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Detalles Bibliográficos
Autores principales: Ostrycharz, Ewa, Wasik, Urszula, Kempinska-Podhorodecka, Agnieszka, Banales, Jesus M., Milkiewicz, Piotr, Milkiewicz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766218/
https://www.ncbi.nlm.nih.gov/pubmed/33352965
http://dx.doi.org/10.3390/ijms21249667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766218/
https://www.ncbi.nlm.nih.gov/pubmed/33352965
http://dx.doi.org/10.3390/ijms21249667

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