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Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors

The long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in treatment of different chronic inflammatory disorders is strongly restricted by their serious gastrointestinal adverse effects. Therefore, there is still an urgent need to search for new, safe, and efficient anti-inflammatory age...

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Detalles Bibliográficos
Autores principales: Szczukowski, Łukasz, Krzyżak, Edward, Zborowska, Adrianna, Zając, Patrycja, Potyrak, Katarzyna, Peregrym, Krzysztof, Wiatrak, Benita, Marciniak, Aleksandra, Świątek, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766220/
https://www.ncbi.nlm.nih.gov/pubmed/33348757
http://dx.doi.org/10.3390/ijms21249623