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Inhibition of Pneumolysin Cytotoxicity by Hydrolysable Tannins

Streptococcus pneumoniae causes invasive infections such as otitis media, pneumonia and meningitis. It produces the pneumolysin (Ply) toxin, which forms a pore onto the host cell membrane and has multiple functions in the pathogenesis of S. pneumoniae. The Ply C-terminal domain 4 mediates binding to...

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Detalles Bibliográficos
Autores principales: Maatsola, Santeri, Kurkinen, Sami, Engström, Marica T., Nyholm, Thomas K. M., Pentikäinen, Olli, Salminen, Juha-Pekka, Haataja, Sauli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766327/
https://www.ncbi.nlm.nih.gov/pubmed/33371182
http://dx.doi.org/10.3390/antibiotics9120930