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Suppression of Pax3–MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide

Paired box gene 3 (Pax3) and cAMP responsive element-binding protein (CREB) directly interact with the cis-acting elements on the promoter of microphthalmia-associated transcription factor isoform M (MITF-M) for transcriptional activation in the melanogenic process. Tyrosinase (Tyro) is a target gen...

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Detalles Bibliográficos
Autores principales: Choi, Yong-Pyo, Kim, Ga Hyun, Kim, Song-Hee, Maeng, Jongseo, Lee, Heesoon, Han, Sang-Bae, Kim, Ki Ho, Kim, Youngsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766340/
https://www.ncbi.nlm.nih.gov/pubmed/33348800
http://dx.doi.org/10.3390/ijms21249631