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Suppression of Pax3–MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide
Paired box gene 3 (Pax3) and cAMP responsive element-binding protein (CREB) directly interact with the cis-acting elements on the promoter of microphthalmia-associated transcription factor isoform M (MITF-M) for transcriptional activation in the melanogenic process. Tyrosinase (Tyro) is a target gen...
Autores principales: | Choi, Yong-Pyo, Kim, Ga Hyun, Kim, Song-Hee, Maeng, Jongseo, Lee, Heesoon, Han, Sang-Bae, Kim, Ki Ho, Kim, Youngsoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766340/ https://www.ncbi.nlm.nih.gov/pubmed/33348800 http://dx.doi.org/10.3390/ijms21249631 |
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