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Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds

During the past several years, the frequency of discovery of new molecular entities based on γ- or δ-lactam scaffolds has increased continuously. Most of them are characterized by the presence of at least one chiral center. Herein, we present the preparation, isolation and the absolute configuration...

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Detalles Bibliográficos
Autores principales: Listro, Roberta, Rossino, Giacomo, Della Volpe, Serena, Stabile, Rita, Boiocchi, Massimo, Malavasi, Lorenzo, Rossi, Daniela, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766352/
https://www.ncbi.nlm.nih.gov/pubmed/33352660
http://dx.doi.org/10.3390/molecules25246023