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Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions

Human transthyretin (hTTR), a serum protein with a main role in transporting thyroid hormones and retinol through binding to the retinol-binding protein, is an amyloidogenic protein involved in familial amyloidotic polyneuropathy (FAP), familial amyloidotic cardiomyopathy, and central nervous system...

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Detalles Bibliográficos
Autores principales: Cotrina, Ellen Y., Vilà, Marta, Nieto, Joan, Arsequell, Gemma, Planas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766448/
https://www.ncbi.nlm.nih.gov/pubmed/33348885
http://dx.doi.org/10.3390/ijms21249640