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Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex

The identification of protein-protein interaction disruptors (PPIDs) that disrupt the YAP/TAZ-TEAD interaction has gained considerable momentum. Several studies have shown that YAP/TAZ are no longer oncogenic when their interaction with the TEAD family of transcription factors is disrupted. The tran...

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Detalles Bibliográficos
Autores principales: Pobbati, Ajaybabu V., Rubin, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766469/
https://www.ncbi.nlm.nih.gov/pubmed/33352993
http://dx.doi.org/10.3390/molecules25246001