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The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents

The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary idea: a heterobifunctional chimera with the capacity of creating an interaction between a prot...

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Detalles Bibliográficos
Autores principales: Coll-Martínez, Bernat, Delgado, Antonio, Crosas, Bernat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766482/
https://www.ncbi.nlm.nih.gov/pubmed/33339292
http://dx.doi.org/10.3390/molecules25245956