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The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents
The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary idea: a heterobifunctional chimera with the capacity of creating an interaction between a prot...
Autores principales: | Coll-Martínez, Bernat, Delgado, Antonio, Crosas, Bernat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766482/ https://www.ncbi.nlm.nih.gov/pubmed/33339292 http://dx.doi.org/10.3390/molecules25245956 |
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