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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

Antazoline (ANT) was recently shown to be an effective and safe antiarrhythmic drug in the termination of atrial fibrillation. However, the drug is still not listed in clinical guidelines. No data on ANT metabolism in humans is available. We used liquid chromatography coupled with tandem mass spectr...

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Detalles Bibliográficos
Autores principales: Giebułtowicz, Joanna, Korytowska, Natalia, Piotrowski, Roman, Kułakowski, Piotr, Latacz, Gniewomir, Szymańska, Ewa, Wiśniowska, Barbara, Polak, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766522/
https://www.ncbi.nlm.nih.gov/pubmed/33353167
http://dx.doi.org/10.3390/ijms21249693