Cargando…
Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry
Antazoline (ANT) was recently shown to be an effective and safe antiarrhythmic drug in the termination of atrial fibrillation. However, the drug is still not listed in clinical guidelines. No data on ANT metabolism in humans is available. We used liquid chromatography coupled with tandem mass spectr...
Autores principales: | Giebułtowicz, Joanna, Korytowska, Natalia, Piotrowski, Roman, Kułakowski, Piotr, Latacz, Gniewomir, Szymańska, Ewa, Wiśniowska, Barbara, Polak, Sebastian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766522/ https://www.ncbi.nlm.nih.gov/pubmed/33353167 http://dx.doi.org/10.3390/ijms21249693 |
Ejemplares similares
-
Magnetic Core–Shell Molecularly Imprinted Nano-Conjugates for Extraction of Antazoline and Hydroxyantazoline from Human Plasma—Material Characterization, Theoretical Analysis and Pharmacokinetics
por: Giebułtowicz, Joanna, et al.
Publicado: (2021) -
Development and Performance Verification of the PBPK Model for Antazoline and Its Metabolite and Its Utilization for Pharmacological Hypotheses Formulating
por: Wiśniowska, Barbara, et al.
Publicado: (2022) -
Determination of Antidepressants in Human Plasma by Modified Cloud-Point Extraction Coupled with Mass Spectrometry
por: Gniazdowska, Elżbieta, et al.
Publicado: (2020) -
Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry
por: Hallin, Erik I., et al.
Publicado: (2022) -
Liquid chromatography–tandem mass spectrometry for clinical diagnostics
por: Thomas, Stefani N., et al.
Publicado: (2022)