G(1) Cell Cycle Arrest and Extrinsic Apoptotic Mechanisms Underlying the Anti-Leukemic Activity of CDK7 Inhibitor BS-181

SIMPLE SUMMARY: Chemotherapy resistance in human T-cell acute lymphoblastic leukemia (T-ALL), an aggressive neoplasm, results in poor prognosis despite advances in treatment modalities. Toward the identification of an effective alternative, in the present study, we elucidated the mechanism underlyin...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Shin Young, Kim, Ki Yun, Jun, Do Youn, Hwang, Su-Kyeong, Kim, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766600/
https://www.ncbi.nlm.nih.gov/pubmed/33352782
http://dx.doi.org/10.3390/cancers12123845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766600/
https://www.ncbi.nlm.nih.gov/pubmed/33352782
http://dx.doi.org/10.3390/cancers12123845

Ejemplares similares