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Therapeutic Angiogenesis by a “Dynamic Duo”: Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle

Therapeutic angiogenesis is a promising strategy for relief of ischemic conditions, and gene delivery was used to stimulate blood vessels’ formation and growth. We have previously shown that intramuscular injection of a mixture containing plasmids encoding vascular endothelial growth factor (VEGF)16...

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Detalles Bibliográficos
Autores principales: Slobodkina, Ekaterina, Boldyreva, Maria, Karagyaur, Maxim, Eremichev, Roman, Alexandrushkina, Natalia, Balabanyan, Vadim, Akopyan, Zhanna, Parfyonova, Yelena, Tkachuk, Vsevolod, Makarevich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766676/
https://www.ncbi.nlm.nih.gov/pubmed/33353116
http://dx.doi.org/10.3390/pharmaceutics12121231