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Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing

The discovery of designer nucleases has made genome editing much more efficient than before. The designer nucleases have been widely used for mechanistic studies, animal model generation and gene therapy development. However, potential off-targets and host immune responses are issues still need to b...

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Detalles Bibliográficos
Autores principales: Lyu, Pin, Wang, Luxi, Lu, Baisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766694/
https://www.ncbi.nlm.nih.gov/pubmed/33371215
http://dx.doi.org/10.3390/life10120366