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Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing
The discovery of designer nucleases has made genome editing much more efficient than before. The designer nucleases have been widely used for mechanistic studies, animal model generation and gene therapy development. However, potential off-targets and host immune responses are issues still need to b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766694/ https://www.ncbi.nlm.nih.gov/pubmed/33371215 http://dx.doi.org/10.3390/life10120366 |