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The Potential of Soluble Human Leukocyte Antigen Molecules for Early Cancer Detection and Therapeutic Vaccine Design

Human leukocyte antigen (HLA) molecules are essential for anti-tumor immunity, as they display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA molecules are primarily studied as peptide-loaded complexes on cell membranes (mHLA) and much less attention is given to th...

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Detalles Bibliográficos
Autores principales: Kessler, Amy L., Bruno, Marco J., Buschow, Sonja I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766713/
https://www.ncbi.nlm.nih.gov/pubmed/33353014
http://dx.doi.org/10.3390/vaccines8040775