The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction

SIMPLE SUMMARY: Both cancer and the chemotherapy used to treat it are drivers of cachexia, a life-threatening body-wasting condition which complicates cancer treatment. Poly-(ADP-ribose) polymerase (PARP) inhibitors are currently being investigated as a treatment against cancer. Here, we present par...

Descripción completa

Detalles Bibliográficos
Autores principales: Campelj, Dean G., Timpani, Cara A., Petersen, Aaron C., Hayes, Alan, Goodman, Craig A., Rybalka, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766767/
https://www.ncbi.nlm.nih.gov/pubmed/33348673
http://dx.doi.org/10.3390/cancers12123810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766767/
https://www.ncbi.nlm.nih.gov/pubmed/33348673
http://dx.doi.org/10.3390/cancers12123810

Ejemplares similares