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Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with an approximate 10% five-year survival rate despite therapy. A plausible reason for this observation may be that other, redundant, immune-suppressive mechanisms are at play. Thus, effective treatment...

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Detalles Bibliográficos
Autores principales: Holokai, Loryn, Chakrabarti, Jayati, Lundy, Joanne, Croagh, Daniel, Adhikary, Pritha, Richards, Scott S., Woodson, Chantal, Steele, Nina, Kuester, Robert, Scott, Aaron, Khreiss, Mohammad, Frankel, Timothy, Merchant, Juanita, Jenkins, Brendan J., Wang, Jiang, Shroff, Rachna T., Ahmad, Syed A., Zavros, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766822/
https://www.ncbi.nlm.nih.gov/pubmed/33348809
http://dx.doi.org/10.3390/cancers12123816