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Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma
SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with an approximate 10% five-year survival rate despite therapy. A plausible reason for this observation may be that other, redundant, immune-suppressive mechanisms are at play. Thus, effective treatment...
Autores principales: | Holokai, Loryn, Chakrabarti, Jayati, Lundy, Joanne, Croagh, Daniel, Adhikary, Pritha, Richards, Scott S., Woodson, Chantal, Steele, Nina, Kuester, Robert, Scott, Aaron, Khreiss, Mohammad, Frankel, Timothy, Merchant, Juanita, Jenkins, Brendan J., Wang, Jiang, Shroff, Rachna T., Ahmad, Syed A., Zavros, Yana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766822/ https://www.ncbi.nlm.nih.gov/pubmed/33348809 http://dx.doi.org/10.3390/cancers12123816 |
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