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Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico

Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide; BUP-g, norbuprenorphine; Nor-BUP, and norbuprenorphine glucuronide; Nor-BUP-g) in opioid use disorder (OUD) patients in Puerto Rico (PR...

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Detalles Bibliográficos
Autores principales: Santiago, Darlene, Mangas-Sanjuan, Victor, Melin, Kyle, Duconge, Jorge, Zhao, Wenchen, Venkataramanan, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766849/
https://www.ncbi.nlm.nih.gov/pubmed/33352843
http://dx.doi.org/10.3390/pharmaceutics12121226