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New Insights into X-Chromosome Reactivation during Reprogramming to Pluripotency

Dosage compensation between the sexes results in one X chromosome being inactivated during female mammalian development. Chromosome-wide transcriptional silencing from the inactive X chromosome (Xi) in mammalian cells is erased in a process termed X-chromosome reactivation (XCR), which has emerged a...

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Detalles Bibliográficos
Autores principales: Panda, Amitesh, Zylicz, Jan J., Pasque, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766869/
https://www.ncbi.nlm.nih.gov/pubmed/33348832
http://dx.doi.org/10.3390/cells9122706