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Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study

Nanomedicines are a novel class of therapeutics that benefit from the nano dimensions of the drug carrier. These nanosystems are highly advantageous mainly within cancer treatment due to their enhanced tumor accumulation. Monolayer tumor cells frequently used in routine preclinical assessment of nan...

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Detalles Bibliográficos
Autores principales: Kudláčová, Júlia, Kotrchová, Lenka, Kostka, Libor, Randárová, Eva, Filipová, Marcela, Janoušková, Olga, Fang, Jun, Etrych, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766879/
https://www.ncbi.nlm.nih.gov/pubmed/33419291
http://dx.doi.org/10.3390/pharmaceutics12121242