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The Degree of Cardiac Remodelling before Overload Relief Triggers Different Transcriptome and miRome Signatures during Reverse Remodelling (RR)—Molecular Signature Differ with the Extent of RR

This study aims to provide new insights into transcriptome and miRome modifications occurring in cardiac reverse remodelling (RR) upon left ventricle pressure-overload relief in mice. Pressure-overload was established in seven-week-old C57BL/6J-mice by ascending aortic constriction. A debanding (DEB...

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Detalles Bibliográficos
Autores principales: Rodrigues, Patrícia G., Miranda-Silva, Daniela, Li, Xidan, Sousa-Mendes, Cláudia, Martins-Ferreira, Ricardo, Elbeck, Zaher, Leite-Moreira, Adelino F., Knöll, Ralph, Falcão-Pires, Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766898/
https://www.ncbi.nlm.nih.gov/pubmed/33353134
http://dx.doi.org/10.3390/ijms21249687