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The Effect of Glutathione Peroxidase-1 Knockout on Anticancer Drug Sensitivities and Reactive Oxygen Species in Haploid HAP-1 Cells

The role of glutathione peroxidases (GPx) in cancer and their influence on tumor prognosis and the development of anticancer drug resistance has been extensively and controversially discussed. The aim of this study was to evaluate the influence of GPx1 expression on anticancer drug cytotoxicity. For...

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Detalles Bibliográficos
Autores principales: Behnisch-Cornwell, Steven, Wolff, Lisa, Bednarski, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766971/
https://www.ncbi.nlm.nih.gov/pubmed/33353055
http://dx.doi.org/10.3390/antiox9121300