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Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

The systematic mutation of histone 3 (H3) genes in model organisms has proven to be a valuable tool to distinguish the functional role of histone residues. No system exists in mammalian cells to directly manipulate canonical histone H3 due to a large number of clustered and multi-loci histone genes....

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Detalles Bibliográficos
Autores principales: Trovato, Matteo, Patil, Vibha, Gehre, Maja, Noh, Kyung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766983/
https://www.ncbi.nlm.nih.gov/pubmed/33353064
http://dx.doi.org/10.3390/cells9122716