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Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals
The systematic mutation of histone 3 (H3) genes in model organisms has proven to be a valuable tool to distinguish the functional role of histone residues. No system exists in mammalian cells to directly manipulate canonical histone H3 due to a large number of clustered and multi-loci histone genes....
Autores principales: | Trovato, Matteo, Patil, Vibha, Gehre, Maja, Noh, Kyung Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766983/ https://www.ncbi.nlm.nih.gov/pubmed/33353064 http://dx.doi.org/10.3390/cells9122716 |
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