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The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-Dependent YAP Pathway

Ciclesonide is an FDA-approved glucocorticoid used to treat asthma and allergic rhinitis. However, whether it has anticancer and anti-cancer stem cell (CSC) effects is unknown. This study focused on investigating the effect of ciclesonide on breast cancer and CSCs and determining its underlying mech...

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Detalles Bibliográficos
Autores principales: Kim, Su-Lim, Choi, Hack Sun, Kim, Ji-Hyang, Lee, Dong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766992/
https://www.ncbi.nlm.nih.gov/pubmed/33352739
http://dx.doi.org/10.3390/molecules25246028