AhR Activation Leads to Alterations in the Gut Microbiome with Consequent Effect on Induction of Myeloid Derived Suppressor Cells in a CXCR2-Dependent Manner

Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent ligand for AhR and a known carcinogen. While AhR activation by TCDD leads to significant immunosuppression, how this translates into carcinogenic signal is unclear. R...

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Detalles Bibliográficos
Autores principales: Neamah, Wurood Hantoosh, Busbee, Philip Brandon, Alghetaa, Hasan, Abdulla, Osama A., Nagarkatti, Mitzi, Nagarkatti, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767008/
https://www.ncbi.nlm.nih.gov/pubmed/33348596
http://dx.doi.org/10.3390/ijms21249613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767008/
https://www.ncbi.nlm.nih.gov/pubmed/33348596
http://dx.doi.org/10.3390/ijms21249613

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