Cargando…

Inhibition of BRD4 Reduces Neutrophil Activation and Adhesion to the Vascular Endothelium Following Ischemia Reperfusion Injury

Renal ischemia reperfusion injury (IRI) is associated with inflammation, including neutrophil infiltration that exacerbates the initial ischemic insult. The molecular pathways involved are poorly characterized and there is currently no treatment. We performed an in silico analysis demonstrating chan...

Descripción completa

Detalles Bibliográficos
Autores principales: Reid, Shelby, Fine, Noah, Bhosle, Vikrant K., Zhou, Joyce, John, Rohan, Glogauer, Michael, Robinson, Lisa A., Scholey, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767067/
https://www.ncbi.nlm.nih.gov/pubmed/33348732
http://dx.doi.org/10.3390/ijms21249620