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Novel Liver X Receptor Ligand GAC0001E5 Disrupts Glutamine Metabolism and Induces Oxidative Stress in Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is the predominant form of pancreatic cancer with a high mortality rate due to the lack of early detection and effective treatment options for advanced diseases. Metabolic reprogramming, a common hallmark of malignant transformation in pancreatic cancer, is cr...

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Detalles Bibliográficos
Autores principales: Srivastava, Shivangi, Widmann, Scott, Ho, Charles, Nguyen, Donovan, Nguyen, Alexis, Premaratne, Asitha, Gustafsson, Jan-Åke, Lin, Chin-Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767092/
https://www.ncbi.nlm.nih.gov/pubmed/33348693
http://dx.doi.org/10.3390/ijms21249622