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SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the most recent global pandemic that has caused more than a million deaths around the world. The spike glycoprotein (S) drives the entry and fusion of this virus and is the main determinant of cell tropism. To exp...

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Detalles Bibliográficos
Autores principales: Havranek, Katherine Elizabeth, Jimenez, Ariana R., Acciani, Marissa Danielle, Lay Mendoza, Maria Fernanda, Reyes Ballista, Judith Mary, Diaz, Darren Austin, Brindley, Melinda Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767099/
https://www.ncbi.nlm.nih.gov/pubmed/33353101
http://dx.doi.org/10.3390/v12121465