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Opening a Novel Biosynthetic Pathway to Dihydroxyacetone and Glycerol in Escherichia coli Mutants through Expression of a Gene Variant (fsaA(A129S)) for Fructose 6-Phosphate Aldolase †

Phosphofructokinase (PFK) plays a pivotal role in glycolysis. By deletion of the genes pfkA, pfkB (encoding the two PFK isoenzymes), and zwf (glucose 6-phosphate dehydrogenase) in Escherichia coli K-12, a mutant strain (GL3) with a complete block in glucose catabolism was created. Introduction of pl...

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Detalles Bibliográficos
Autores principales: Guitart Font, Emma, Sprenger, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767278/
https://www.ncbi.nlm.nih.gov/pubmed/33348713
http://dx.doi.org/10.3390/ijms21249625