Biased Ligands Differentially Shape the Conformation of the Extracellular Loop Region in 5-HT(2B) Receptors

G protein-coupled receptors are linked to various intracellular transducers, each pathway associated with different physiological effects. Biased ligands, capable of activating one pathway over another, are gaining attention for their therapeutic potential, as they could selectively activate benefic...

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Detalles Bibliográficos
Autores principales: Denzinger, Katrin, Nguyen, Trung Ngoc, Noonan, Theresa, Wolber, Gerhard, Bermudez, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767279/
https://www.ncbi.nlm.nih.gov/pubmed/33419260
http://dx.doi.org/10.3390/ijms21249728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767279/
https://www.ncbi.nlm.nih.gov/pubmed/33419260
http://dx.doi.org/10.3390/ijms21249728

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