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Comparison of the Zebrafish Embryo Toxicity Assay and the General and Behavioral Embryo Toxicity Assay as New Approach Methods for Chemical Screening

The movement away from mammalian testing of potential toxicants and new chemical entities has primarily led to cell line testing and protein-based assays. However, these assays may not yet be sufficient to properly characterize the toxic potential of a chemical. The zebrafish embryo model is widely...

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Detalles Bibliográficos
Autores principales: Achenbach, John C., Leggiadro, Cindy, Sperker, Sandra A., Woodland, Cindy, Ellis, Lee D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767334/
https://www.ncbi.nlm.nih.gov/pubmed/33371320
http://dx.doi.org/10.3390/toxics8040126