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TGFβ1 Suppressed Matrix Mineralization of Osteoblasts Differentiation by Regulating SMURF1–C/EBPβ–DKK1 Axis

Transforming growth factor β1 (TGFβ1) is a major mediator in the modulation of osteoblast differentiation. However, the underlying molecular mechanism is still not fully understood. Here, we show that TGFβ1 has a dual stage-dependent role in osteoblast differentiation; TGFβ1 induced matrix maturatio...

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Detalles Bibliográficos
Autores principales: Nam, Bora, Park, Hyosun, Lee, Young Lim, Oh, Younseo, Park, Jinsung, Kim, So Yeon, Weon, Subin, Choi, Sung Hoon, Yang, Jae-Hyuk, Jo, Sungsin, Kim, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767413/
https://www.ncbi.nlm.nih.gov/pubmed/33371439
http://dx.doi.org/10.3390/ijms21249771