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Running to Stand Still: Naive CD8(+) T Cells Actively Maintain a Program of Quiescence

CD8(+) T cells play a pivotal role in clearing intracellular pathogens and combatting tumours. Upon infection, naïve CD8(+) T cells differentiate into effector and memory cells, and this program is underscored by large-scale and coordinated changes in the chromatin architecture and gene expression....

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Detalles Bibliográficos
Autores principales: Bennett, Taylah J., Udupa, Vibha A. V., Turner, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767439/
https://www.ncbi.nlm.nih.gov/pubmed/33371448
http://dx.doi.org/10.3390/ijms21249773