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Running to Stand Still: Naive CD8(+) T Cells Actively Maintain a Program of Quiescence
CD8(+) T cells play a pivotal role in clearing intracellular pathogens and combatting tumours. Upon infection, naïve CD8(+) T cells differentiate into effector and memory cells, and this program is underscored by large-scale and coordinated changes in the chromatin architecture and gene expression....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767439/ https://www.ncbi.nlm.nih.gov/pubmed/33371448 http://dx.doi.org/10.3390/ijms21249773 |